Extended Data Fig. 2: Functional characterization of CsmA.

a, Acyloin-type natural products (1–3) isolated from C. sp. PKU-MA01392. b, HPLC analyses of CsmA-catalyzed reactions at different time points with IPA (S2) and HPPA (S3) as the substrates, and NaBH4 reduction of compound 1. The colours of the HPLC peaks corresponds to different substrates or products. c, The production of compounds 1, 4a, and 4b from CsmA catalysis.