Fig. 4: The SorCS1-associated haplotypes and their effect on behaviour in the F₂ population.

a, A network of the SorCS1-associated haplotypes in the tame and aggressive populations. The sizes of the circles are scaled relative to the frequency of the haplotype in both populations combined, and the centre of the circle is coloured to show the relative frequencies of the haplotype in either population (tame being green and aggressive being red). The outer circle of the three major haplotypes (olv, trq and lav) follows the colouring in b. The length of the lines between the haplotypes is scaled relative to the number of genotypes for individual markers that differ between the haplotypes, ranging from 1 to 3. The black node is the calculated median vector from the Network 5 run. b, Cumulative distributions of the scores for the behavioural phenotype D.PC1 among F₂ individuals homozygous for the three main haplotypes: olv, lav and trq. The primary tame haplotype, olv, is shown in olive green, and the most common aggressive haplotypes, lav and trq, are shown in purple and blue, respectively. The points on the lines are individual F₂ foxes.