Extended Data Fig. 5: Predicted protein structures for genes containing amino acid changes associated with tree health status under ADB pressure.
From: Genomic basis of European ash tree resistance to ash dieback fungus
The protein structures to the left were more common in damaged trees, and those to the right were more common in healthy trees. Variant amino acids are coloured in magenta and indicated with a black arrowhead. (a) Gene FRAEX38873_v2_000003260, a BED finger-NBS-LRR resistance protein, where position 157 is a leucine (left) versus tryptophan (right) variant. Two ATP molecules are shown in orange to indicate the location of nucleotide binding sites. (b) Gene FRAEX38873_v2_000164520, a F-box/kelch-repeat, where position 13 is a glutamine (left) versus arginine (right) variant. (c) FRAEX38873_v2_000180950, a Protein DAMAGED DNA-BINDING, where position 99 is a proline (left) versus leucine (right) variant. DNA molecules are shown in orange docked at the proteins’ DNA binding sites. (d) Gene FRAEX38873_v2_000116110, a 60S ribosomal protein L4-1, where position 251 is an arginine (left) versus glycine (right) variant, position 285 is a methionine (left) versus arginine (right) variant, position 287 is an asparagine (left) versus lysine (right) variant and position 297 is a threonine (left) versus alanine (right) variant.
