Extended Data Fig. 1: Plots of cancer cell content, sequencing depth and mutation load for the paired BL/PD biopsies from 21 patients in the Prospect-C trial.
From: Mutational signatures impact the evolution of anti-EGFR antibody resistance in colorectal cancer
a, Estimated cancer cell contents of paired BL and PD samples. A 1:1 ratio line has been added for reference. b, Mutation load vs. mean sequencing depth for all BL and PD samples. p-value from Spearman’s test. A linear regression line has been added for reference. c, Mutation load vs. cancer cell content for all BL and PD samples. p-value from Spearman’s test. A linear regression line has been added for reference.
