Extended Data Fig. 1: Examples of CpG sites where methylation levels are non-linearly related with chronological age.
From: Hibernation slows epigenetic ageing in yellow-bellied marmots
Each plot includes the site identification in the Mammalian array and its location relative to the closest transcriptional start site. The CpG sites coordinates were estimated based on the alignment of Mammalian array probes to yellow-bellied marmot (Marmota flaviventer) genome assembly. Trend lines represent the GAM smooth function. R and p-values are based on the Pearson correlation of the CpGs’ methylation level and age in marmots.
