Extended Data Fig. 6: Transposon–chromatin gene fusions.
From: A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution

a, Number of candidate fusion genes classified by the level of gene model validation evidence, based on contiguity of the gene model over the genome assembly (that is lack of poly-N stretches in the genomic region between the TE- and chromatin-associated domains), evidence of expression, and evidence of contiguous expression (see inset at the right). b, Summary of candidate gene fusions within each chromatin-associated gene family, divided by gene family. For each gene, we indicate their similarity to known TE families, presence of TE-associated domains, the evidence of gene model validity, and information on their gene structure (whether they are monoexonic or are located in clusters with other fusion genes). Source data available in Supplementary Table 6. c, Number of species with at least one valid fusion, divided by gene family. d, Mapping positions of RNA-seq reads supporting candidate gene-transposon fusions (selected examples from Fig. 5e). For each fusion, we show reads spanning the region along the spliced transcript that fully covers the transposon-associated domains (highlighted in green), the chromatin-associated domains, and the inter-domain region. Uninterrupted stretches of mapped positions between domains indicate the validity of a domain co-occurrence. For clarity purposes, reads mapping entirely within a single domain have been excluded from this visualization.