Extended Data Fig. 2: Histone post-translational modifications.
From: A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution
a, Proteomics detection coverage (% of amino acids), number of hPTMs and number of hPTMs per covered position, for the best-covered histone in each species in our proteomics survey. b, Number of samples in which each histone-matching peptide with post-translational modifications (peptide spectral matches defined by Proteome Discoverer) has been identified, per species. For each species, we report the percentage of modified peptides found in more than one replicate. c, Number of samples in which histone-matching modified peptide has been identified, across all the samples from this study. The tree pie charts represent these distributions for all hPTMs, acetylations, and methylations. d, Evidence of hPTM conservation in the major histone variants H2A.Z and macroH2A (conserved positions only), as well as any position in the linker histones H1.
