Extended Data Fig. 6: Comparison of optic lobe neurons across species.
(a, b) Pairwise AUROC scores showing the cross-species transcriptional similarity of OL clusters between Monomorium and Drosophila. Drosophila OL cell clusters from two independent studies that focus exclusively on the Drosophila optic lobes, namely Kurmangaliyev et al41 and Özel et al42, were used for the analyses. Comparisons with AUROC scores > 0.5 are presented as exact values. (c) Correspondence of OL clusters between Monomorium and Drosophila as predicted by the AUROC scores in panel a and panel b. Each line links a Monomorium OL cluster to its top hit among the Drosophila OL clusters according to AUROC scores, with line thickness being proportional to the score. A second hit is plotted as well, when the difference between the top and second AUROC score was less than 0.05. (d, e) Violin plots showing the expression of Nlg2 across the Drosophila OL clusters. Dashed boxes indicate the T4/T5 neurons.
