Extended Data Fig. 1: Quality control metrics of the M. pharaonis single-nucleus RNA-seq datasets.

(a-d) The number of transcripts (a, b) and genes (c, d) detected in the nuclei from each phenotype-specific biological replicate (a, c) and from each adult phenotype after combing biological replicates (b, d). The number of nuclei per category is shown above each box. For all box plots, the horizontal thick lines denote median values, the boxes show the range between the 25th and 75th percentile, and the whiskers represent 1.5× the interquartile range. (e) The correlation of gene expression between bulk RNA-seq data and snRNA-seq data.