Extended Data Fig. 2: Classification of the M. pharaonis clusters into major cell types. | Nature Ecology & Evolution

Extended Data Fig. 2: Classification of the M. pharaonis clusters into major cell types.

From: A single-cell transcriptomic atlas tracking the neural basis of division of labour in an ant superorganism

Extended Data Fig. 2

(a) Dot plot showing the expression of neuronal (Syt1, nSyb, and fne) and glial markers (Glaz, bdl, and repo) across the M. pharaonis cell clusters. (b) Dot plot showing the expression of representative markers that define the major cell types. Gene symbols shown in bold font denotes known markers reported by previous studies in other insect species. Gene symbols shown in regular font denotes novel markers obtained from this study. (c) PCA based on average expression profile of each cluster. Clusters are coloured according to cell type category. (d-e) Pairwise transcriptional similarity (measured by AUROC scores) of cell clusters from Monomorium and Drosophila (d), and from Monomorium and Harpegnathos (e). The cell-cluster dendrogram trees were generated by hierarchical clustering using the Ward’s minimum variance method with the distance defined as 1-AUROC. KC: Kenyon cell; OL: optic lobe; PR: photoreceptor; OPN: olfactory projection neuron; MN: monoaminergic neuron; AST: astrocyte; EG: ensheathing glia; CG: cortex glia; SG: surface glia.

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