Extended Data Fig. 2: Genome scans of genetic diversity within populations and differentiation between populations across chromosome housing major venom gene families (SVMPs, SVSPs, and PLA2s) in CV2 and CO2 populations.
From: The roles of balancing selection and recombination in the evolution of rattlesnake venom
a Sliding windows of nucleotide diversity (π) in C. viridis (CV2) and C. oreganus (CO2) populations and sequence divergence (dxy) and relative differentiation (Fst) between CV1 and CV2 and between CO1 and CO2 across Chromosome 9 (top panels), and in the SVMP region (bottom panels). b π, dxy, and Fst across Chromosome 10 (top), and in the SVSP region (bottom). c π, dxy, and Fst across Chromosome 15 (top), and in the PLA2 region (bottom). Shaded points in top panels show estimates in 10 kb windows and lines show estimates in 100 kb windows. In bottom panels in a and b, shaded points show estimates in 1 kb windows, and lines show estimates in 10 kb windows. In bottom panels in c, shaded points show estimates in 250 bp windows and lines are estimates in 1 kb windows. The regions housing venom genes are shaded in grey in all panels. Chromosome-specific and genome-wide mean values for each statistic are represented by blue and red dashed horizontal lines. The locations of individual venom genes are shown as blue boxes (bottom panels). The non-venom homologue PLA2gIIE is shown in light purple. Gaps in measurements are locations that were masked due to significant evidence of copy-number variation between C. viridis and C. oreganus.
