Extended Data Fig. 2: Phylogenomic analysis of chordates and gene duplication rates across metazoan evolution.

a, Bayesian Inference tree of 31 chordate species was built using a protein alignment (see Methods). All nodes were recovered with a posterior probability of 1. Cyclostome monophyly was unequivocally supported. Scale bar indicates 0.1 substitutions per site. b, c, The exact number of gene duplication events inferred using OrthoFinder2 with greater than 50% support (b) and the number of events per million years per branch (c) are shown. In each case, the colour of the branch represents the value according to the key on the upper-left of each pane. Hagfish is highlighted in red font in all panels.