Extended Data Fig. 6: The relationship between the number of KO gene families encoded on a genome and the total number of protein-coding genes.
From: The nature of the last universal common ancestor and its impact on the early Earth system
LOESS regression of the number of KOs per sampled genome against the number of proteins encoded for per sampled genome. We used the inferred relationship for modern prokaryotes to estimate the total number of protein-coding genes encoded by LUCA based on reconstructed KO gene family content, as described in the main text. Shaded area represents the 95% confidence interval.
