Extended Data Fig. 10: Results of non-Wright—Fisher -models of the northern elephant seal population omitting deleterious mutations (‘neutral’ models).
From: Genomic and fitness consequences of a near-extinction event in the northern elephant seal
Results are shown for different sets of five non-Wright-Fisher neutral simulations that varied in the carrying capacity (K) of the population during the bottleneck. Nc values were simulated over time (shown in generations), starting from one generation before the bottleneck to the present day, for: a, K = 50. b, K = 100. c, K = 250. d, K = 500 and e, K = 1,000. The thick green lines represent average Nc across the five simulations (light green lines). The results of the simulations including deleterious mutations (the same as in Fig. 5) are shown for comparison. The thick dark grey line represents the average Nc of the simulations where the population did not go extinct (light grey lines). The orange points (joined by orange lines) indicate empirical Nc estimates from Bartholomew & Hubbs27, Le Boeuf & Bonnell28, Stewart et al.29 and Lowry et al.30. The vertical dashed red line indicates the onset of the bottleneck.
