Extended Data Fig. 1: ‘Difficult’ Simulation of genome evolution.
From: EdgeHOG: a method for fine-grained ancestral gene order inference at large scale
Each dot represents one of the 99 ancestral levels in a species tree with 100 extant genomes. The x-axis gives the Relative Evolutionary Divergence of an ancestral node (0 for the root, near to 1 close to the leaves). The top row’s y-axis gives the precision of each algorithmic step of edgeHOG and of Agora at each ancestral level, measuring the proportion of predicted edges that are true edges in the simulated ancestral genome. The bottom row’s y-axis shows recall, that is, the proportion of true edges predicted by each method. Parameters of the simulation are given in the Supplementary Information.
