Fig. 2: Meerkat MHC class II diversity and neutral genetic evolution over time. | Nature Ecology & Evolution

Fig. 2: Meerkat MHC class II diversity and neutral genetic evolution over time.

From: Twenty years of tuberculosis-driven selection shaped the evolution of the meerkat major histocompatibility complex

Fig. 2

a, The relative abundance of MHC-DRB alleles among 1,567 sampled meerkats. The dashed line indicates the 5% threshold. Coloured boxes represent alleles with data available for all study years. b, The total number of uninfected (dark grey), TB-exposed (blue) and TB-positive (orange) individuals with MHC genotype information compared with the rest of uncharacterized meerkats in the population (light grey). c, Change in relative abundance (termed frequency; mean ± s.d.) of the six Susu-DRB alleles present in at least 5% of the population in each year since 1999. The dashed line and shaded area represent neutral genetic diversity (measured as Hexp; mean ± sd). d, Estimated annual evenness of MHC (black) and microsatellite (grey) allele frequencies. e, Fitted regression (±95% CIs) of genetic differentiation (that is, pairwise Fst) of the meerkat population over time estimated from microsatellite (grey) and MHC data (black).

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