Fig. 3: MHC-DRB allele association with TB susceptibility. | Nature Ecology & Evolution

Fig. 3: MHC-DRB allele association with TB susceptibility.

From: Twenty years of tuberculosis-driven selection shaped the evolution of the meerkat major histocompatibility complex

Fig. 3

a, A heat map displaying higher (that is, positive association) and lower (that is, negative association) likelihood of observing TB signs in meerkats with different MHC-DRB alleles based on co-occurrence analysis (*P < 0.05, **P < 0.01). b,c, Effect sizes (±95% CIs; n = 1,497) for all explanatory variables included in the generalized linear mixed-effects model including the MHC allele Susu-DRB*13 (b) and visualization of nonlinear effects of Susu-DRB*13 (green) on TB susceptibility over time (c). Significant effects are in blue (lower likelihood of developing TB signs) and red (higher likelihood of developing TB signs).

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