Extended Data Fig. 9: Validation of NDTE framework.
From: Revisiting the global workspace orchestrating the hierarchical organization of the human brain
Following the work of Seth, Chorley and Barrett1, we constructed a directional network with five nodes and simulated BOLD timeseries by using a Hopf model. b, This network is represented by the simple directional coupling 5×5 matrix. The generative Hopf model was run 10 times with 1200 timepoints sampled at TR = 0.72 s. We then validated the NDTE framework by applying this to the simulated data (using the same lag of 10 and 100 surrogates as in the analysis of the empirical data). c, The figure shows the recovered NDTE uncorrected matrix without using surrogates and aggregation of p-values. d, In contrast, the figure shows the results of using surrogates and aggregation of p-values and corrected for multiple comparisons. The NDTE framework is clearly able to recover the original couplings.
