Fig. 4: Miami plot for GWAS of the PNA and IDK factors.

Miami plot of the resulting P values from a GWAS of the PNA factor (top) and the IDK factor (bottom) for the 360,628 UK Biobank participants included in this study. The x axis is the chromosomal position and the y axis represents the –log10 of the corresponding P value for each location measured in the genome with a two-sided test. The dashed red line marks the threshold for genome-wide significance (P = 5 × 10−8), which corrects for multiple hypothesis testing.