Table 1 Genome-wide significant loci for EduYears in EAS population

From: Shared genetic architectures of educational attainment in East Asian and European populations

Chr

Start

End

Credible set ID

Credible set size

Total PIP

N of significant variantsa

SNP with maximum PIP

Maximum PIP

A1

Effect size

A1 Freq

Marginal P value

Gene

Annotation

2

161,721,597

162,351,261

1

6

0.96

6

rs10930013

0.26

A

−0.021

0.42

7.80 × 10−10

TANK

Intron

4

180,613,679

181,136,169

1

4

0.95

4

rs2871133

0.36

C

−0.020

0.53

3.54 × 10−9

NA

NA

5

93,838,858

94,392,030

1

20

0.95

19

rs255347

0.11

T

0.022

0.73

5.70 × 10−9

MCTP1

Intron

5

106,947,725

107,455,182

1

2

0.96

2

rs7708343

0.62

A

−0.021

0.32

4.46 × 10−9

FBXL17

Intron

6

27,515,505

29,611,229

1

13

0.95

3

rs9461540

0.47

G

−0.027

0.17

6.19 × 10−10

GABBR1

Upstream gene

6

27,515,505

29,611,229

2

6

0.96

6

rs16893804

0.40

G

−0.028

0.22

5.62 × 10−12

NA

NA

10

103,385,878

104,057,295

1

27

0.96

18

rs11191157

0.60

A

−0.023

0.22

2.34 × 10−8

C10orf76

Intron

17

42,899,988

43,438,117

1

10

0.95

10

rs12936234

0.20

C

0.020

0.47

4.28 × 10−9

NMT1

Intron

  1. Abbreviations: A1 Freq, frequency of A1; A1, effect allele; Chr, chromosome; N, number; NA, not available. Gene symbols are italicized.
  2. aNumber of genome-wide significant variants with P value of a two-sided test <5 × 10−8.
  3. Base pair position is based on the human genome assembly GRCh37 (hg19).
  4. ‘Credible set ID’: the ID of credible sets used to identify different credible sets in the same region.
  5. ‘Gene’: the genes affected by the variant using the Variant Effect Predictor tool.
  6. ‘Annotation’: the consequence of variants on the protein sequence using the Variant Effect Predictor tool.
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