Extended Data Fig. 9: Factor loadings for the mood and anxiety disorders latent variable.

Including 8 psychiatric disorders (major depressive disorder [MDD], bipolar disorder, posttraumatic stress disorder [PTSD], generalized anxiety disorder [GAD], obsessive-compulsive disorder [OCD], social phobia, agoraphobia, and panic disorder) as indicators for a single M/AD latent variable demonstrated acceptable fit (RMSEA = 0.02, CFI = 0.98, SRMR = 0.13). All item loadings were significant and ranged from 0.11 for MDD to 1.00 for PTSD.