Extended Data Fig. 4: Potential change of PEDOT:PSS channel following dopamine oxidation.
From: A biohybrid synapse with neurotransmitter-mediated plasticity
a, Schematic of the experimental setup for monitoring the potential of the PEDOT:PSS channel during device operation using a potentiostat operated in open circuit voltage mode. The channel is connected to a grounded working electrode (WE) and the potential is monitored in reference to a saturated silver/silver chloride (Ag/AgCl) reference electrode (RE) immersed in the electrolyte. b, The channel conductance (GCh), potential (EWE) and gate voltage pulses (VG) over time showing no change in GCh or EWE in the absence of dopamine (DA) in response to VG pulses. After DA is added to solution, GCh and EWE both decrease in response to VG pulses, showing the change in GCh (ΔGCh) is due to the potential change in the channel following oxidation (ΔEWE). At t = 275 s, we exchange the solution with fresh PBS containing no DA to show that both ΔEWE and ΔGCh are properties of the channel, not the solution.
