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MICROBIOME

Homing in on 12,13-diHOME in asthma

Nature Microbiology volume 4, pages 1774–1775 (2019)Cite this article

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12,13-diHOME produced by the gut microbiome promotes an asthma-like immunophenotype in the lungs of a murine experimental model. Accordingly, the metabolite is elevated in neonates who developed asthma during childhood, potentially providing a biomarker for early risk prediction and a novel therapeutic target.

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Authors and Affiliations

  1. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK

    Christopher J. Stewart

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  1. Christopher J. Stewart
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Correspondence to Christopher J. Stewart.

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The author declares no competing interests.

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Stewart, C.J. Homing in on 12,13-diHOME in asthma. Nat Microbiol 4, 1774–1775 (2019). https://doi.org/10.1038/s41564-019-0599-y

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