Extended Data Fig. 5: Body weight changes of inoculated and exposed ferrets during the transmission study.
Ferrets were intranasally inoculated with 106 PFU of WT- KK001-I38 (H1N1pdm, n=3), MUT-KK001-I38T (H1N1pdm, n=3), WT-GR117-I38 (H3N2, n=5), or MUT-GR117-I38T (H3N2, n=5). One day later, naïve ferrets (exposed ferrets, n=3, n= 3, n=5, and n=5 for WT-KK001-I38, MUT-KK001- I38T, WT-GR117-I38, and MUT-GR117-I38T, respectively) were each placed in a cage adjacent to an infected ferret. a, Body weights of inoculated ferrets were measured on Days 0, 1, 3, 5, 7, 9, and 11 post-infection. b, Body weights of exposed ferrets were measured on Days 0, 3, 5, 7, 9, 11, and 13 post- exposure. Data are presented as the mean percentages of the starting weight ± SD.
