Extended Data Fig. 7: Rapid diagnostic of healthy preterm P103 using SQK-RAD004.

(a) Taxonomic profiles detected for preterm P103. Figure legend comprises the 8 most abundant taxa obtained. Further information on specific taxa read counts can be found in Supplementary Table 3. (b) Correlation plot of normalised assigned reads from P103 at 1h of sequencing (x-axis) and at 6h of sequencing (y-axis). Taxa n=131, with log transformed Pearson’s r = 0.99. The grey region either side of fit line represents 95% confidence intervals. (c) Heat map displaying number of CARD database hits detected among the most common groups of antibiotic resistance genes found in preterm P103. Top and lower panel indicate the hours since sequencing started and the number of reads analyzed within this timeframe. Further information on the specific AMR genes classified can be found in Supplementary Table 4. (d) Walkout results reported by NanoOK RT software. Results shown are from independent hits (bacterial host hit ⋝ 50 bp from the AMR hit) at 6 hours of sequencing.