Fig. 2: Longitudinal study on preterm infant P10 using MinION and Illumina sequencing.

a, Timeline diagram of preterm P10 indicating the times of faecal sample collection (P10N, P10R and P10V), duration of antibiotic and probiotic treatment and relevant clinical observations. The diagram is divided into weeks and the dots represent days within the timescale. The blue dots represent the days of probiotic treatment; the red dots represent the days of antibiotic treatment; the black squares represent the time points for sample collection; and the letter H represents the transfer of the preterm infant to another hospital. b, Correlation plot of normalized species abundance in taxonomic assignments of Illumina (x axis) and MinION (y axis) data for sample P10N, with log-transformed Pearson’s r = 0.95 (taxa n = 92). The values for P10R and P10V were 0.90 and 0.94, respectively. The grey region either side of the fit line represents the 95% CIs. c, Taxonomic profiles at time points P10N, P10R and P10V, as assigned by MEGAN. The top row corresponds to the results obtained using MinION sequencing; the bottom row displays the results obtained using Illumina HiSeq. The legend comprises the 12 most abundant taxa obtained. Further information on all taxa and corresponding read counts can be found in Supplementary Table 3.