Extended Data Fig. 9: Antibiotic resistance profiles of K. pneumoniae in contact mice matches antibiotic resistance profile of K. pneumoniae administered to index mice. | Nature Microbiology

Extended Data Fig. 9: Antibiotic resistance profiles of K. pneumoniae in contact mice matches antibiotic resistance profile of K. pneumoniae administered to index mice.

From: Commensal Bacteroidetes protect against Klebsiella pneumoniae colonization and transmission through IL-36 signalling

Extended Data Fig. 9

a, Fecal K. penumoniae burden in samples from neonatal contact mice before and after cohousing with K. penumoniae OXA-48 (resistant to azithromycin and ampicillin and sensitive to kanamycin) colonized index mice (n=6,7 animals) (a). b,c Fecal K. penumoniae burden in samples from adult contact mice before and after cohousing with K. penumoniae OXA-48 colonized index mice (n=6,7 animals) (b) or K. penumoniae ST258 (resistant to kanamycin and ampicillin and sensitive to gentamycin) colonized index mice (n=6,7 animals) (c). Culture media was supplemented with kanamycin, ampicillin, gentamycin and azithromycin were indicated (at 50 μg/mL). ND is none detected (the limit of detection for K. pneumoniae in feces = 103 CFU/g), horizontal lines indicate mean values.

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