Extended Data Fig. 10: Changes in transcriptional activity (KEGG orthologies) in complex microbial communities in response to NAE treatment. | Nature Microbiology

Extended Data Fig. 10: Changes in transcriptional activity (KEGG orthologies) in complex microbial communities in response to NAE treatment.

From: Growth effects of N-acylethanolamines on gut bacteria reflect altered bacterial abundances in inflammatory bowel disease

Extended Data Fig. 10

Log2 relative expression is shown for bacterial families contributing to a selection of KEGG orthologies in samples from chemostats A and B treated with DMSO control, individual NAEs, a combination of all four NAEs (denoted as NAE-mix), or oleic acid (OA). Family-level relative expression values were computed at the species level, averaged over replicates, and then averaged within-family while weighting by species abundance. Unknown (“x”) values represent cases where a function’s DNA and/or RNA abundance were zero for a given stratification (resulting in non-finite log2 relative expression). Col_sort refers to the measure (treatment, time or chemostat) used to order the metadata columns.

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