Extended Data Fig. 6: Mass spectrometry analysis of Pak1 triggered NLRP3 phosphorylation. | Nature Microbiology

Extended Data Fig. 6: Mass spectrometry analysis of Pak1 triggered NLRP3 phosphorylation.

From: Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Extended Data Fig. 6

a-c, Fragmentation spectra of human NLRP3 peptides showing phosphorylation of Ser-163, Ser-198 and Thr-659. d, Representation of NLRP3 domain structure and sequence alignment of NLRP3 ortholog peptides surrounding phosphorylated residues identified by mass spectrometry. The phosphorylated residues are in bold red.

Source data

Back to article page