Extended Data Fig. 1: Longitudinal viral RNA determination following SARS-CoV-2 infection in rhesus macaques.
From: Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
Viral RNA (log10 copies/mL measured by RT-PCR in buccopharyngeal swab (a), plasma (b) and urine (c) of rhesus macaques longitudinally. Subgenomic viral RNA (log10 copies/gram of lung tissue was measured at endpoint in rhesus macaques and (d) and Baboons (e). (Rhesus: Old-Triangle, Young-Diamonds; Baboon: Old-Inverted triangle, Young- Square, Colors represent individual animals, Supplementary Table 1). (n=12). Data are represented as mean+ SEM. Two way Repeated-measures ANOVA with Geisser-Greenhouse correction for sphericity and Tukey’s post hoc correction for multiple-testing (GraphPad Prism 8) was applied. Correlations with Spearman’s rank test between Log10 viral RNA copy number in Lung with BAL and NS (f) and corresponding values for Spearman’s rank correlation coefficient (g) and P values (h). Coloring scheme for f – BAL (magenta circle), NS (teal square).
