Extended Data Fig. 4: Lineage B panel RBD sequence features. | Nature Microbiology

Extended Data Fig. 4: Lineage B panel RBD sequence features.

From: Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

Extended Data Fig. 4

a, Amino acid sequences corresponding to SARS-spike residues 317 through 500 were aligned with ClustalW. Contact points between SARS-spike and human ACE2 are indicated with an (*). Clade 2 sequences are shown as compared to clade 2 As6526, with identical residues indicated with a (.) and sites that vary between clade 2 viruses highlighted in purple. Loop deletions are highlighted in orange. b, Amino acid alignment of 2019-nCoV RBD and consensus RBD sequences for clade 1 and 2 and BM48-31 (clade 3). Loop deletions are highlighted in orange.

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