Extended Data Fig. 8: Acetate concentration in meconium samples.
From: Bacterial colonization reprograms the neonatal gut metabolome
a, The acetate concentration was higher in samples obtained after 16 hours with low human DNA and other groups, and was not different in samples collected before vs. after 16 hours with high human DNA (two-sided Mann-Whitney test, p-values indicated above bars, n1 = 30 collected before 16 hours, n2 = 21 after 16 hours with human DNA > 75%, n3 = 30 after 16 hours with human DNA < 75%). Boxes in indicate the median and interquartile distance, whiskers indicate maximum and minimum data points within 1.5 times the interquartile range, points represent values outside this range. b, Acetate concentration increased with 16 S copy number per gram feces (two-sided test of Spearman correlation, ρ = 0.33, P = 0.002, n = 84). The blue line indicates the linear regression estimate, and the grey area indicates the 95% confidence interval. The dashed vertical line indicates the lower limit of detection for 16 S qPCR measurements. Samples with high acetate concentration are labeled. c, Acetate concentration increased with time since birth (two-sided test of Spearman correlation, ρ = 0.27, P = 0.02, n = 81). The dashed vertical line indicates 16 hours after birth.
