Extended Data Fig. 6: Human transcriptome profiles response to fungal damage.
a, Levels of LDH release by epithelial cells upon the damage by four fungal pathogens 24 hpi. All values are presented as mean ± SD of n = 3 independent experiments. b, PCA plot of human samples interacting with non-viable and viable fungal species, including C. albicans ece1Δ/Δ. The plot is obtained using the RUVg function of RUVseq with k = 1 (see Extended Data Fig. 7 for plots with alternative k values). Labels of the data points correspond to sample identifiers, where ‘reseq’ indicates that the sample was sequenced more than once (see Supplementary Table 1 for details). ‘non-viable’ indicates host samples interacting with non-viable fungal cells; ‘ece1Δ/Δ’ indicates host samples interacting with C. albicans ece1Δ/Δ.
