Extended Data Fig. 7: RboP-WTA impairs S. epidermidis 1457 binding to A549 but promotes its binding to HUVECs.
a, The scavenger receptor inhibitor polyinosinic acid (poly-I) inhibits the increased binding of S. epidermidis E73∆IJLM2 to A549. b, RboP-WTA production in the GroP-WTA S. epidermidis 1457 decreases its binding to the human airway epithelial cell line A549 but promotes its binding to HUVECs (c). Means ± s.d. of three independent experiments are shown in (a-c). One-way ANOVA with Dunnett’s post-test (two-sided) was used to analyze significant differences vs. PBS condition in (a). Significant differences (P ≤ 0.05) were calculated by unpaired t-test between wt and the hybrid strain in (b) and (c).
