Extended Data Fig. 4: Antibiotic resistance genes identified from 11.8 million viral proteins.
From: Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome

a-b, Viral genes with putative beta-lactamase domains identified based on hits to the Pfam and KEGG databases, respectively. c-e, Resistance genes (including beta-lactamases) identified using Resfinder, AMRfinder, or the Resistance Gene Identifier (RGI), respectively. f, Overlap of resistance genes identified by Resfinder, AMRfinder, and RGI. Most viral proteins identified with putative beta-lactamase domains are not confirmed as antibiotic resistance genes.