Extended Data Fig. 1: Description of patient cohort, samples obtained, analyses performed and sequencing depth.

Schematic representation of the measurements obtained in this cohort of 589 critically ill COVID-19 patients. Top barplots summarize median number of reads obtained per sample of 142 independent subjects prior to filtering (Pre) and after filtering (Post). Bottom barplots show the median number of reads annotated to different microbial kingdoms in each sample. *SARS-CoV-2, Human with Lungs, RNA and DNA images were created with BioRender.com. **NYU Langone Health is the official brand from NYU Langone Health.