Fig. 3: Deletion profiling using MIP sequencing of pfhrp2 (chromosome 8), pfhrp3 (chromosome 13) and flanking regions applied to 375 field samples. | Nature Microbiology

Fig. 3: Deletion profiling using MIP sequencing of pfhrp2 (chromosome 8), pfhrp3 (chromosome 13) and flanking regions applied to 375 field samples.

From: Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia

Fig. 3

Samples are grouped by subtelomeric structural profile, with control strains denoted CT, as labelled along the right y axis. LC (low concentration) and HC (high concentration) controls include mixtures of 1% HB3, 10% DD2, 89% 3D7 strains at densities of 250 and 1,000 parasites per µl, respectively. Columns represent each MIP target segment, rows represent individual samples and the colour scale represents log10(UMI) depth-of-coverage at each location. Columns are labelled by the midpoint of each probe’s target region.

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