Fig. 5: Faecal abundances of infant-type Bifidobacterium species and ILA associate with AhR activity.
a,b, Scatter plot of subject- and age-adjusted linear mixed-model β coefficients (versus FDR-corrected P values, two-sided tests) obtained from associations between AhR activity of faecal water (n = 111) from selected CIG infants (Fig. 4d–f, n = 11) in a reporter cell line assay and absolute abundance of faecal bacterial taxa (relative abundance >0.1%, n = 40, circles) (a) or quantities of aromatic amino acid metabolites (n = 19, triangles) (b) measured in the same samples. Coloured circles/triangles mark taxa/metabolite measures that are significantly positively (red) or negatively (blue) associated with AhR activity within an FDR-corrected P of 0.1 (dashed line). ILA, indolelactic acid; Tyr, tyrosine.
