Extended Data Fig. 3: A common clonotype of anti-RBD antibodies with the same binding mechanism. | Nature Microbiology

Extended Data Fig. 3: A common clonotype of anti-RBD antibodies with the same binding mechanism.

From: Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

Extended Data Fig. 3

a. RBD/AZD8895 crystal structure. b. RBD/S2E12 cryo-EM structure. c. RBD/COV2-2381 homology model generated with Structuropedia25. COV2-2072 encodes an N-linked glycosylation sequon in the HCDR3, indicated by the gray spheres, which was modeled using the GlyProt webserver. d. RBD/COV2-2072 homology model generated with Structuropedia25. e. Overlay of the RBD/AZD8895 crystal structure (a) and RBD/S2E12 cryo-EM structure (b).

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