Extended Data Fig. 1: Impact of culture positivity and TPN administration on fungal and bacterial microbiota dynamics during allo-HCT, related to Fig. 1.

(a) Comparison of fungal density per gram of stool (n = 246 pre-transplant samples and n = 978 post-transplant samples) and (b) fungal diversity (n = 251 pre-transplant samples and n = 1028 post-transplant samples) between the pre- (days -10 to -1) and the post-transplant period (days 0 to 30). (c) Comparison of bacterial density per gram of stool (n = 241 pre-transplant samples and n = 976 post-transplant samples) and (d) diversity (n = 245 pre-transplant samples and n = 939 post-transplant samples) between the pre- and post-transplant period. Statistical tests (a–d): Two-sided P-values issued from generalized estimating equations with patient ID as cluster variable are shown. The upper whisker represents the maximum value or the 75th percentile value plus 1.5 times the IQR, whichever is larger. The lower whisker represents the minimum value or the 25th percentile value minus 1.5 times the IQR.