Extended Data Fig. 9: JQ1 reduces BRD4 occupancy on CCND1 gene promoter.

Chromatin immunoprecipitation (ChIP) with anti-BRD4 antibody or control IgG, and qPCR for the promoters of CCND1 gene. T-REx-293 cells were treated with JQ1 and stimulated with TNF-α. Means + s.d. (n = 6 per condition from two independent experiments). Statistical significance was determined by the Student’s t-test.