Extended Data Fig. 6: Comparison of viral loads between vaccinated and unvaccinated cases based on hospitalization status.

Grouped box-and-whisker plots and swarm plots showing the differences in mean cycle threshold (Ct) values between vaccinated (n = 32) and unvaccinated (n = 362) cases overall given hospitalization due to COVID-19 (n = 57) or nonhospitalized status (n = 337). There were no significant differences in viral loads (inversely proportional to the Ct value) in the pairwise comparisons. For the box-and-whisker plots, the box outlines denote the interquartile ratio (IQR), the solid line inside the box denotes the median, the dotted line inside the box denotes the mean (μ) Ct value, and the whiskers outside the box extend to the minimum and maximum fold enrichment points. Welch’s t-test was used for significance testing.