Extended Data Fig. 8: Genes encoding inner membrane complex genes with significantly reduced expression in HDP1 knockout parasites have upstream HDP1 binding sites.

Remaining HDP1 binding sites upstream of genes encoding inner membrane complex proteins. Histogram track shows the significance of enrichment by position. Regions of significant enrichment are shown as boxes with black vertical lines indicating peak summits within each peak. Instances of Motif A, Motif B, or overlapping motifs within peaks are shown in red, blue and purple, respectively. Genes encoded in forward or reverse orientation are shown in blue or red, respectively. Combined estimate of two biologically independent samples.