Extended Data Fig. 3: Loss of HDP1 does not alter the sexual commitment frequency or Stage I gametocyte viability.
(a) The sexual commitment frequency (day 5 gametocytes per day 1 ring stages) is not significantly affected in halo-hdp1 and ∆hdp1 parasites. Data are presented as mean values ± s.e.m. of n = 3 biologically independent samples. (b) Mitochondrial membrane potential of gametocytes (GCs), as measured by DilC(1)5 staining, indicates similar viability on day 2, but not days 5 or 10, for NF54 (orange) and ∆hdp1 (green) gametocytes. Flow cytometry plots are representative of n = 2 biologically independet samples.
