Extended Data Fig. 4: Inducible knockdown of HDP1 reduces gametocyte maturation in early but not late gametocytes. | Nature Microbiology

Extended Data Fig. 4: Inducible knockdown of HDP1 reduces gametocyte maturation in early but not late gametocytes.

From: The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites

Extended Data Fig. 4

(a) Percentage of falciform gametocytes on Day 10 in response to 5 mM glucosamine on days 1-5, 3-8, 5-10, or in the absence of glucosamine for hdp1-Ty1 or hdp1-glmS parasites. Data are presented as mean values ± s.e.m of n = 2 biologically independent samples. (b) Representative morphology of hdp1-glmS gametocytes in response to 5 mM glucosamine on days 1-5, 3-8, 5-10, or in the absence of glucosamine, among two independent experiments. Scale bar, 3 μm.

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