Fig. 1: Neutralization titres of plasma from individuals receiving CoronaVac and BNT162b2 vaccines.
a,b, pVNT50 of recipients of the CoronaVac vaccine (n = 53) and of the BNT162b2 vaccine (n = 56) against (a) pseudotype Wuhan-Hu-1 reference strain (wild-type) or (b) D614G (B.1), Alpha (B.1.1.7), Gamma (P.1), Lambda (C.37) and Delta (B.1.617.2) variants. The statistical significance of the difference between the neutralization was calculated by Wilcoxon matched-pairs signed-rank test. Two-tailed P values are reported. Geometric mean titres and 95% CIs are indicated. c,d, Box plots indicate the median and interquartile range of pVNT50 for each SARS-CoV-2 pseudotype for the CoronaVac (c) and BNT162b2 (d) groups. Factor changes are shown in parentheses as the difference of the geometric mean titre in pVNT50 compared with that of the wild-type pseudotyped virus. Statistical analyses were performed with the two-tailed Kruskal–Wallis test after adjustment for the false discovery rate. Geometric mean titres are indicated. e,f, Results are shown as the difference in neutralization titres of matched samples for each SARS-CoV-2 pseudotype in the CoronaVac (e) and BNT162b2 (f) groups. P values for comparison of the pVNT50 were calculated with the Wilcoxon signed-rank test.
