Extended Data Fig. 5: Most species depleted in the rUTI gut are also depleted in the IBD gut. | Nature Microbiology

Extended Data Fig. 5: Most species depleted in the rUTI gut are also depleted in the IBD gut.

From: Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women

Extended Data Fig. 5

We compared discriminatory taxa in rUTI women to those in IBD patients using data from adult participants in the HMP2 study33. For each study, we fitted mixed effects models to standardized Metaphlan2 relative abundances as a function of categorical disease group (rUTI or IBD respectively, vs. each study’s control cohort), including covariates for race and antibiotic use. The disease group coefficients are plotted against each other for each species, with circle pairs representing the average relative abundance in each study. Species with uncorrected p values <0.05 in either study are labelled. Species not present in at least 10% of samples in either study are excluded. IBD comprises patients with either CD or UC.

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