Extended Data Fig. 3: The C-terminus of DddAI abuts DddA. | Nature Microbiology

Extended Data Fig. 3: The C-terminus of DddAI abuts DddA.

From: Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase

Extended Data Fig. 3

X-ray crystal structure of the DddAI–DddA complex in ribbon and surface representation, respectively. The C-terminal amino acid of DddAI (Leu123) is colored red and shown in space filling representation to highlight its position against the surface of DddA. The figure highlights how a C-terminal epitope fusion to DddAI would weaken the interaction with DddA due to steric clash.

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