Fig. 1: Sensitive isolation of all SARS-CoV-2 VOC and key VUI over the period of February to May 2021. | Nature Microbiology

Fig. 1: Sensitive isolation of all SARS-CoV-2 VOC and key VUI over the period of February to May 2021.

From: Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia

Fig. 1

a, Rapid end-point titres versus average Ct values (Ct values are averages of the Ct values across the viral genes detected (that is, primarily E, RdRP and N)) recorded using the HAT-24 cell line for rapid and sensitive isolation of SARS-CoV-2. Variant B.1.517.1 (open blue circles) is used herein for comparison, with samples derived from community spread in Australia from December 2020 to the end of January 2021 (n = 50). b–d, Rapid appearance of viral CPE (see large spherical viral syncytia) following overnight (c) versus 48 h (d) culture with a swab positive for the VOC Beta (b is mock uninfected control). CPE appearance is representative of all VOC. Scale bars in b–d, 10 μm.

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