Extended Data Fig. 8: Pathway comparison between the BT inositol lipid cluster and the predicted alternative inositol lipid pathway.
From: Characterization of inositol lipid metabolism in gut-associated Bacteroidetes
At left, the BT-like inositol lipid synthesis pathway defined in this work. At right, the putative inositol lipid synthesis pathway genomically predicted for multiple Bacteroidetes spp., with predicted enzymes (in purple) from the Bacteroides vulgatus genome (NCBI reference sequence NC_009614.1). Inositol glycerophospholipids are on a gray background with green text; inositol sphingolipids are on a white background with red text. Branching patterns of BT DHC-based lipids and B. vulgatus lipids are predicted and not confirmed. SPT = serine palmitoyltransferase; MIPS = myo-inositol phosphate synthase; PIPPh = phosphatidylinositol phosphate phosphatase.
